Pdf laugierhunziker syndrome is an infrequent benign and acquired condition of the lips, oral mucosa and nails. Report of one case laugier hunziker syndrome is a rare benign. Although this syndrome is considered a benign disease with no systemic manifestations or malignant. Extended mucocutaneous pigmentation has become a recognized feature of laugierhunziker syndrome. Melanotic macular hyperpigmentation has been observed on the neck, the thorax, the abdomen, the dorsal and lateral aspects of the fingers, the palms and soles, the genitalia, the perineum, the perianal skin, and the anal mucosa of patients with laugier hunziker syndrome. We present the case of a 63yearold female with progressive, asymptomatic hyperpigmentation of buccal mucosa and a 7year history of hyperpigmentation in several fingernails. Jun 27, 2019 extended mucocutaneous pigmentation has become a recognized feature of laugier hunziker syndrome.
Laugier hunziker syndrome is a rare disorder that is characterized by adultonset hyperpigmented macules of the lips, oral cavity, and fingertips. They appear as macular lesions less than 5 mm in diameter. A series of six cases is presented, including two patients from the same family. The laugierhunziker syndrome lhs is an acquired, benign pigmentary skin condition involving the oral mucosa, often associated with longitudinal. Pdf on oct 1, 2016, mohammad adil and others published laugier. Laugierhunziker syndrome is a rare benign condition characterized by diffuse oral hyperpigmentation associated with pigmentation of the nails. Laugierhunziker syndrome lhs was initially described in 1970 as acquired, benign hyperpigmented macules of the lips and buccal mucosa frequently associated with longitudinal melanonychia. If you do not have it you can download adobe reader free of charge. Laugier hunziker syndrome is a benign mucocutaneous pigmentary disorder that mainly affects the oral mucosa and nails. E nata a soregno il 24 gennaio 1977 da madre olandese e padre svizzerotedesco. Champion rh, burton jl, burns da, breathnach sm, eds.
Three pediatric patients are reported and literature case report are discussed. An external file that holds a picture, illustration, etc. Laugier hunziker syndrome is a rare benign condition characterized by diffuse oral hyperpigmentation associated with pigmentation of the nails. Abstract laugier hunziker syndrome is a rare acquired disorder. Pdf most of the documents on the racgp website are in portable document format pdf. Idiopathic lenticular mucocutaneous pigmentation or laugier. Laugierhunziker syndrome in endocrine clinical practice in.
It is a diagnosis of exclusion, and other systemic conditions should be excluded prior to making a diagnosis. Laugier hunziker syndrome is a rare acquired pigmentary disorder that is characterized by idiopathic mucocutaneous pigmentation that may be associated with longitudinal melanonychia. Most text books on oral pathology and oral medicine do not include lhs as a cause of oral hyperpigmentation probably because of its benign. Laugierhunziker syndrome is a rare acquired disorder characterized by diffuse hyperpigmentation of the oral mucosa and longitudinal melanonychia in adults. Laugierhunziker syndrome lhs is a rare, benign and acquired disorder characterized by. Laugier hunziker syndrome is a rare, acquired disorder characterized by lenticular hyperpigmentation of the oral mucosa and longitudinal melanonychia. Laugierhunziker syndrome is an infrequent benign and acquired condition of the lips, oral mucosa and nails. The laugierhunziker syndrome lhs is an acquired, benign pigmentary. Jun 27, 2019 laugier hunziker syndrome lhs was initially described in 1970 as acquired, benign hyperpigmented macules of the lips and buccal mucosa frequently associated with longitudinal melanonychia. Pdf laugierhunziker syndrome is a rare acquired disorder characterized by diffuse. Una vita apparentemente perfetta michelle hunziker libro. Laugierhunziker syndrome is a rare, acquired disorder characterized by lenticular hyperpigmentation of the oral mucosa and longitudinal melanonychia. The laugier hunziker syndrome lhs is an acquired, benign pigmentary skin condition involving the oral mucosa, often associated with longitudinal melanonychia.
Summary laugier hunziker syndrome is an infrequent benign and acquired condition of the lips, oral mucosa and nails. Laugierhunziker syndrome is an uncommon benign pathology characterized by hyperpigmentation of the oral mucosa, lips and acral region. We describe a 43yearold white woman with the clinical and histological features of laugier hunziker. Ayoub n, barete s, bouaziz jd, le pelletier f, frances c. Laugierhunziker syndrome lhs is a rare acquired benign macular hyperpigmentation of the lips and oral mucosa which is often associated with longitudinal melanonychia. The laugierhunziker syndrome europe pmc article europe pmc. Abstract laugierhunziker syndrome is a rare benign acquired disorder of unknown pathogenesis, firstly described in 1970, characterized by macular mucocutaneous hyperpigmentation frequently associated with longitudinal melanonychia. If you continue browsing the site, you agree to the use of cookies on this website. These files will have pdf in brackets along with the filesize of the download.
Laugierhunziker syndrome is considered to be a benign disease with no systemic manifestation or malignant potential. To open a pdf file you will need compatible software such as adobe reader. Laugier hunziker syndrome lhs is a rare acquired benign macular hyperpigmentation of the lips and oral mucosa which is often associated with longitudinal melanonychia. If the inline pdf is not rendering correctly, you can download the pdf file here. The laugierhunziker syndrome lhs is an acquired, benign pigmentary skin condition involving the oral mucosa, often associated with longitudinal melanonychia. Laugier hunziker syndrome lhs is an infrequent disorder, characterized by brown macular hyperpigmentation as a grayish brown lentiginous macules of about 5 mm, of the lips and oral. Iperpigmentazione a tipo sindrome di laugierhunziker insorta in corso di polichemioterapia antineoplastica.
Extended mucocutaneous features have been observed since that original description, including macular pigmentation of the genitalia. The most likely diagnosis is laugierhunziker syndrome lhs. Longitudinal melanonychia is present in the majority of cases. Additional conjunc tival and penile pigmentation in laugierhunziker syndrome. Melanotic macular hyperpigmentation has been observed on the neck, the thorax, the abdomen, the dorsal and lateral aspects of the fingers, the palms and soles, the genitalia, the perineum, the perianal skin, and the anal mucosa of patients with laugierhunziker syndrome. Laugierhunziker syndrome lhs is a rare mucocutaneous disorder. The syndrome must be included in the differential diagnosis of diffuse oral pigmentation to exclude other conditions with systemic implications.
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